BSR Core faculty assist Massey researchers in developing and designing projects, writing biostatistical sections of the grant proposal, developing data collection instruments, performing biostatistical analyses at interim points and, at the end of a trial, developing new methodologies if needed, and assisting writing the results from the trials for publication.
Methodologic research in biostatistics originates from the shared resource’s collaborations and consultations with Massey researchers. Examples include design of Phase II trials with retrospective biomarkers, bivariate twin methodology for multiple cancers, and microarray data analysis methods.
BSR Core faculty provide advice on biostatistical issues involved in the design, conduct, and analysis of research projects. Examples include preparing a study plan from the requirements of the statistical design, developing appropriate randomization and stratification procedures, managing data and assisting with the conduct of pre-clinical and clinical studies through provision of interim analyses.
The BSR conducts training through seminars and individual sessions with investigators. BSR Core faculty members also train postdoctoral scientists and clinical fellows through the clinical research and biostatistics training track.
Participation in monitoring system
The BSR Core faculty actively participates in Massey’s Protocol Review and Monitoring System (PRMS). All investigator-initiated protocols must now involve a biostatistician and be reviewed by an independent biostatistician.