Virginia Commonwealth University

VCU Massey Cancer Center

Transgenic/Knock-out Mouse Facility


The primary purpose of the L.T. Christian III Transgenic/Knock-out Mouse Facility is to provide an efficient and economical means for producing genetically modified mice for research members of VCU Massey Cancer Center. Genetically modified mice (including transgenic mice, in which customized genes are introduced into the genome, or “knock-out/knock-in” mice, in which endogenous genes within the mouse genome are specifically inactivated or modified) have become an indispensable tool in cancer research. The utility of such models ranges from studies of the basic biology of tumorigenesis and progression to the creation of genetically accurate tumor models for the evaluation of novel therapeutic approaches. 


All publications that include results, services or products generated by the VCU Massey Cancer Center Shared Resources must include the following acknowledgement in the manuscript:

"Services and products in support of the research project were generated by the VCU Massey Cancer Center Transgenic/Knock-out Mouse Facility, supported, in part, with funding from NIH-NCI Cancer Center Support Grant P30 CA016059."

PubMed Central (PMC) ID numbers are required for those publications that use CCSG-supported shared resources. All of Massey Cancer Center's shared resources are supported by the CCSG. Information to assist you with this process can be found here