New drug combination in preclinical laboratory studies effectively kills brain and breast cancer, and inhibits Ebola, influenza and many other viruses and superbug bacteria
Scientists at Virginia Commonwealth University Massey Cancer Center have developed a drug combination that kills brain and breast cancer stem cells in preclinical laboratory studies. The breakthrough drug combination also prevents viruses, including Ebola, from replicating and makes “superbug” bacteria vulnerable to common antibiotics. The combination works by targeting a protein known as GRP78, according to a study published in the Journal of Cellular Physiology.
Massey clinical researcher receives leadership award from the National Cancer Institute
The National Cancer Institute (NCI) recently awarded a Cancer Clinical Investigator Team Leadership Award (CCITLA) to VCU Massey Cancer Center oncologist and cancer researcher Andrew Poklepovic, M.D. The CCITLA recognizes and supports outstanding mid-career clinical investigators at NCI-designated cancer centers whose leadership, participation and activities help promote cancer research through clinical trials.
Pre-clinical study shows potential to increase the effectiveness of leukemia treatments by blocking the production of a nuclear protein that affects chemotherapy response and tumor initiation
Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 (CHD4) may help increase the effectiveness of first-line treatments for acute myeloid leukemia (AML), a particularly lethal blood cancer that is increasing in incidence among older adults.
NCI grant allows Massey to expand community outreach efforts
VCU Massey Cancer Center was recently awarded a grant by the National Cancer Institute (NCI) to support the expansion of Massey’s outreach initiatives through the NCI’s National Outreach Network (NON) Community Health Educator (CHE) program. NON is one of two multidisciplinary programs within the NCI’s Integrated Networks Program (INP) that connects at-risk and underserved communities with NCI research, training and outreach efforts through trained CHEs located at partnering research sites.
Twitter chat on prostate cancer
Last week, the National Cancer Institute and the Men’s Health Network co-hosted a Twitter chat on prostate cancer. The discussion focused on the future of treatments for the disease, and VCU Massey Cancer Center hematologist-oncologist Asit Paul, M.D., Ph.D., with nurse practitioner Gwen Parker, M.S., FNP-C weighed in as the moderator posed a series of questions.