Research breakthrough could halt melanoma metastasis
In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin. More than 1 million cases of skin cancer are diagnosed each year in the U.S., and melanoma is the deadliest form. With further research, the approach used by the scientists could lead to targeted therapies that stop metastasis in melanoma and potentially a broad range of additional cancers.
Physician-researcher receives 2012 Alliance Research Grant
VCU Massey Cancer Center hematologist-oncologist Beata Holkova, M.D., was recently awarded an Alliance Research Grant to support her work involving drug combinations to battle B-cell lymphomas. The grant was presented at this year’s Alliance Group Meeting in Chicago, Illinois. Holkova is a Harrison Endowed Scholar and member of the Developmental Therapeutics research program at VCU Massey Cancer Center and assistant professor of hematology-oncology and internal medicine at the VCU School of Medicine.
Massey partners to bring health information service to Petersburg library
Petersburg residents can now access current and accurate health information at their local library. The Petersburg Healthy Living and Learning Center at the Petersburg Central Library hosted a grand opening on October 1, 2012, in conjunction with National Health Literacy Month. The Center is the result of a partnership among the Library, Virginia Commonwealth University Massey Cancer Center and Crater Health District.
Researchers harness the immune system to improve stem cell transplant outcomes
A novel therapy in the early stages of development at Virginia Commonwealth University Massey Cancer Center shows promise in providing lasting protection against the progression of multiple myeloma following a stem cell transplant by making the cancer cells easier targets for the immune system.
Translational research: from bench to bedside
Massey’s science-driven translational research – moving scientific discoveries from the laboratory into real-world patient applications – is one of the many reasons the National Cancer Institute recently awarded Massey a five-year renewal as one of only two NCI-designated Cancer Centers in Virginia. Often described as “bench-to-bedside” research, translational research involves several stages, including clinical trials, where consenting patients are given drugs, surgical procedures, devices or other interventions to treat cancer and are then closely monitored to determine side effects, effectiveness and other key findings.